Ekudleni kwansuku zonke,i-magnesium bekulokhu kungumsoco othathwa kancane, kodwa ngesidingo esikhulayo sezithako zokudla okunomsoco kanye nokudla okusebenzayo, imakethei-magnesium kanye ne-magnesium L-threonate idonse ukunakwa okwengeziwe. Njengamanje, i-magnesium L-threonate isetshenziswa kakhulu kuamaphilisi, iziphuzo esezilungele ukuphuzwa, ama-snack bar,amaswidi athambileneminye imikhiqizo.
2.I-Magnesium L-threonate, enezinga eliphezulu lokumunca kanye nokugcinwa
I-Magnesium (Mg) iyiminerali yesibili egcwele kakhulu emangqamuzaneni futhi iyi-cofactor yokusabela kwe-enzymatic okungaphezu kuka-300. Ngakho-ke, i-magnesium nayo iyisakhi esibalulekile semisebenzi eminingi ye-metabolic emzimbeni. Idlala indima ebalulekile ekukhiqizeni amandla eselula, ukukhiqizwa kwamaprotheni, ukulawulwa kwezakhi zofuzo, nokugcina ukusebenza okuvamile kwamathambo namazinyo.
I-Magnesium ayigcini nje ngokuvula imisebenzi yama-enzyme amaningi emzimbeni, kodwa futhi ilawula ukusebenza kwezinzwa, igcina ukuzinza kwesakhiwo se-nucleic acid, ilawula izinga lokushisa lomzimba, futhi ithinte imizwelo yabantu. Ibandakanyeka cishe kuzo zonke izinqubo ze-metabolic emzimbeni womuntu. I-Magnesium iyinsada ekutholakaleni kokudla. Okusanhlamvu, okusanhlamvu, nokudla okunamaqabunga amnyama kuqukethe i-magnesium, njengesipinashi neklabishi. Izithako ezivame kakhulu ezengeziwe ze-magnesium supplements zihlanganisai-magnesium glycinate, i-magnesium L-threonate, i-magnesium malate, i-magnesium taurine, i-magnesium oxide, i-magnesium chloride/i-magnesium lactate, i-magnesium citrate, i-magnesium sulfate, njll. Phakathi kwabo, i-magnesium L-threonate iyinhlanganisela ye-magnesium ene-bioavailability ephezulu.
Umthombo wesithombe:pixabay
Ngo-2010, ososayensi be-MIT bashicilela isihloko ephephabhukwini i-Neuron, bebika ukuthi bathole inhlanganisela ye-magnesium ebizwa ngokuthi i-L-magnesium threonate (Magtein®), engaguqula ngempumelelo i-magnesium ihanjiswe kumaseli obuchopho. Ucwaningo lubonisa ukuthi i-magnesium L-threonate imuncwa kangcono futhi igcinwe uma iqhathaniswa neminye imithombo ye-magnesium, njenge-chloride, i-citrate, i-glycinate, ne-gluconate.
Izinzuzo ze-3.Magnesium L-threonate
Izinzuzo ze-Magnesium L-threonate Njengenhlanganisela entsha ye-magnesium ye-bioavailable, i-magnesium L-threonate iya ngokuya iqashelwa ngamandla ayo okuthuthukisa ukusebenza kwengqondo nokuthuthukisa inkumbulo. Ucwaningo oluningi lubonise ukuthi i-magnesium L-threonate ingahambisa ngempumelelo i-magnesium kumaseli e-neuronal kuwo wonke umgoqo wegazi nobuchopho, ngaleyo ndlela ithuthukise i-neuroplasticity, ithuthukise inkumbulo namakhono okuqonda, futhi yehlise ukukhathazeka nokucindezeleka.
Inkumbulo ethuthukisiwe: Kumodeli yegundane, uSlutsky et al. ibike ukuthi i-magnesium L-threonate supplementation yenyanga eyodwa yandise ukugxila kwe-magnesium ebuchosheni bamagundane amancane namadala futhi yathuthukisa kakhulu inkumbulo nekhono lokufunda. I-Magnesium L-threonate iphinde yathuthukisa ukutholakala kwenkumbulo kumagundane asebekhulile. I-Magnesium L-threonateisengezo akuthinti isisindo somzimba, amandla okuzivocavoca, noma amanzi nokudla okudlayo. Indlela yokusebenza ye-magnesium L-threonate ekusebenzeni kwengqondo ingase ibe ngokuvula ama-NMDA receptors, okwandisa ukuminyana kwe-synaptic futhi kuthuthukise inkumbulo. Olunye ucwaningo lwathola ukuthi ukuphathwa komlomo kwesikhathi eside kwe-magnesium L-threonate kungavimbela futhi kubuyisele inkumbulo yesikhashana (STM) kanye nokushoda kwamandla esikhathi eside (LTP) kuma-synapses e-hippocampal CA3-CA1 okubangelwa ukulimala kwezinzwa (SNI).
Ngaphezu kwalokho, ukuphathwa komlomo kwesikhathi eside kwe-magnesium L-threonate kuvimbela ukulawulwa kwe-TNF-α ku-hippocampus, okuye kwaboniswa ukuthi ibalulekile ekulahlekeni kwenkumbulo. Ukuphathwa ngomlomo kwe-magnesium L-threonate kungase kube indlela elula nephumelelayo yokuthuthukisa ukusilela kwenkumbulo.
Ikhwalithi yokulala ethuthukisiwe:Olunye ucwaningo lwathola ukuthi izifundo ezengeza nge-magnesium L-threonate zithole ikhwalithi yokulala ethuthukisiwe, kanye nokucaca okuthuthukisiwe kwengqondo nokusebenza komzimba phakathi nosuku. Kuhle ukuqaphela ukuthi izinzuzo zokulala ze-magnesium L-threonate zimayelana nokuthuthukisa ikhwalithi yokulala okujulile kanye nokuqapha kwengqondo lapho uvuka kunokusiza abantu ukuthi balale ngokushesha.
Ukuqonda okuthuthukisiwe:I-Hypoxia ivimbela ukungena kwe-glutamate, i-neurotransmitter yobuchopho enkulu ehlobene eduze nokusebenza kwengqondo, kumangqamuzana obuchopho, futhi impendulo yokuqala yamaseli ku-cortical hypoxia incike ku-glutamate. I-Magnesium L-threonate ikhulisa ukugxila kwe-magnesium ion ebuchosheni futhi ithuthukise ukusebenza kwengqondo. Ucwaningo luthole ukuthi i-magnesium L-threonate ingalawula ukuvezwa kwe-glutamate transporter EAAT4, futhi inomphumela omuhle ekusindeni kwe-neuron futhi yehlise i-cerebral infarction ku-zebrafish ngemva kwe-hypoxia.
4.Imikhiqizo ehlobene ye-magnesium L-threonate
Ekudleni kwansuku zonke, i-magnesium ibilokhu ingumsoco ongalinganiswanga, kodwa ngesidingo esikhulayo sezithako zokudla okunomsoco nokudla okusebenzayo, imakethe ye-magnesium ne-magnesium L-threonate idonse ukunakwa okwengeziwe. Njengamanje, i-magnesium L-threonate isetshenziswa kakhulu kuamaphilisi, iziphuzo esezilungele ukuphuzwa, ama-snack bar,izinsini nokunyeimikhiqizo.
Isikhathi sokuthumela: Feb-02-2025