Muva nje, i-Akay Bioactives, inkampani yase-US ekhiqiza izithako zokudla okunempilo, ishicilele ucwaningo olungahleliwe, olulawulwa yi-placebo mayelana nemiphumela yesithako sayo se-Immufen™ ku-rhinitis encane ye-allergy, inhlanganisela ye-turmeric kanye notamatisi odakiwe waseNingizimu Afrika. Imiphumela yocwaningo ikhombisile ukuthi i-turmeric kanye neziqeshana ezidakayo zaseNingizimu Afrika zingaqeda i-rhinitis ye-allergy.
I-Allergic Rhinitis, inkinga yezempilo yabantu abangaphezu kwezigidi ezingu-400
I-allergic rhinitis (AR) yisifo esivame ukuvuvukala kwepheshana lokuphefumula eliphezulu esithinta abantu abangaphezu kwezigidi ezingu-400 emhlabeni jikelele, futhi ukusabalala kwaso kukhuphuke eminyakeni embalwa edlule. Izici zaso zifaka phakathi ukuthimula, ikhala eligobhozayo, ukuminyana kwamakhala, kanye nokulunywa kwamehlo, impumulo, kanye nolwanga. Ngokuvamile kuhambisana nezinye izimo ezifana ne-asthma, i-conjunctivitis, kanye ne-sinusitis, okungaholela ekwehleni kwekhwalithi yokuphila, ukungasebenzi kahle kwengqondo, ukusebenza kabi komsebenzi, kanye nekhwalithi yokulala ephansi.
Izindlela ezibalulekile ekubangeleni i-allergic rhinitis ukungalingani phakathi kwamaseli e-T osizo ohlobo 1 (Th1) namaseli e-T osizo ohlobo 2 (Th2), kanye nokungalingani phakathi kokuzivikela komzimba okungokwemvelo nokuguqukayo okuhlanganisa amaseli aveza i-antigen, ama-lymphocyte namaseli e-T.
Ukwelashwa kwe-allergy rhinitis kuvame ukwenziwa ngama-antihistamine noma ama-decongestant ekhaleni, futhi yize ama-antihistamine esethuthukisiwe ezizukulwaneni eziningana, angase abangele imiphumela emibi efana nekhanda elibuhlungu, ukukhathala, ukozela, i-pharyngitis, kanye nesiyezi. Ukwelashwa ngamakhambi manje sekuvela njengomuthi ophephile noma ohlukile wokuthuthukisa kanye/noma ukuphatha izimo ze-AR.
Utamatisi Odakiwe waseTurmeric kanye nowaseNingizimu Afrika Uthuthukisa Kakhulu I-AR
Ocwaningweni olwanyatheliswa yi-Akay Bioactives, ababambiqhaza abangu-105 babelwa ngokungahleliwe ukuthola i-turmeric extract ne-South African drunk tomato extract (i-CQAB, i-capsule ngayinye ye-CQAB ifaka i-95 ± 5 mg ye-curcumin kanye ne-125 mg ye-South African drunk tomato extract), i-bioavailable curcumin (i-CGM, i-capsule ngayinye ye-CGM iqukethe i-250 mg ye-curcumin), noma i-placebo kabili ngosuku izinsuku ezingu-28. Ngokuhlaziya i-covariance (ANCOVA), i-CQAB yatholakala ukuthi inciphisa kakhulu izimpawu ezihlobene ne-allergy rhinitis uma kuqhathaniswa ne-CGM kanye ne-placebo. Uma kuqhathaniswa ne-placebo: ukuminyana kwamakhala kwehliswe ngo-34.64%, impumulo egobhozayo ngo-33.01%, impumulo elumayo ngo-29.77%, ukuthimula ngo-32.76%, kanye ne-Total Nasal Symptom Score (TNSS) ngo-31.62%; Uma kuqhathaniswa ne-CGM: ukuminyana kwamakhala kwehliswe ngo-31.88%, impumulo egobhozayo ngo-53.13%, impumulo elumayo ngo-24.98%, ukuthimula ngo-2.93%, kanye nokwehla ngo-25.27% ku-Total Nasal Symptom Score (TNSS).
I-monograph ye-Ayurvedic uDhanwantari Nighantu ukhuluma nge-turmeric njengendlela yokuzivikela kanye nokwelapha i-rhinitis. I-eggplant edakiwe isetshenziselwa ukwelapha ukuminyana kwamakhala (ukuyeka ukukhwehlela nobunzima bokuphefumula) kanye nokuthuthukisa amandla. Ukuhlanganiswa kwalezi zitshalo ezimbili kungaba nomphumela we-synergistic pharmacological futhi ngaleyo ndlela kuthuthukiswe i-allergy rhinitis. I-Akay Bioactives ishicilele ucwaningo oluthole ukuthi ikhono le-curcumin lokuguqula isimiso somzimba lincike ekusebenzisaneni kwayo nezinhlobo ezahlukene ze-immune modulator, njenge-B cells, T cells, dendritic cells, natural killer cells, neutrophils, kanye ne-macrophages; nokuthi izithako ezisebenzayo ze-South African drunkenness tomato lactone kanye ne-The active components of South African hepatica (hepatica lactone and hepatica lactone glycosides) zingasebenzisa imiphumela yazo ye-immunomodulatory ngokuhlanganisa nokusebenzisa ama-macrophages.
Abantu abahlushwa izimpawu ze-allergy rhinitis bavame ukuba nekhwalithi yokulala ephansi, okungaholela ekwehleni kwekhono lokufunda, ukwehla kokufunda/ukukhiqiza, ngaleyo ndlela kube nekhwalithi yokuphila ephansi. Ngenkathi i-curcumin ku-turmeric inganciphisa ukubambezeleka kokulala futhi yandise isikhathi sokulala emagundwini; ukudakwa i-lactone ekudakweni kwaseNingizimu Afrika kunganciphisa ukucindezeleka futhi kuthuthukise ukulala. Ngakho-ke, kungacatshangwa ukuthi imiphumela yokusebenzisana kwezidakamizwa zaseNingizimu Afrika kanye ne-curcumin kungenzeka ukuthi inikeze imiphumela yokukhuthaza ukulala ye-CQAB.
Ngaphezu kwalokho, abahlanganyeli ocwaningweni olushicilelwe babike amazinga akhuphukile okuphazamiseka kwemizwelo, ukukhathala, kanye nokwehla kwamandla ekuqaleni kocwaningo. Futhi i-curcumin ithuthukise kakhulu isimo sengqondo esingesihle. Ngokufanayo, i-South African Drunken Tomato Extract yaziwa ngokunciphisa ukucindezeleka nokwandisa amandla, ngaleyo ndlela ithuthukisa ikhwalithi yokuphila kanye nekhono lokusebenza emsebenzini. Phakathi kwezinye izinto, i-South African Drunken Tomatoes inganciphisa umsebenzi we-hypothalamic-pituitary-adrenal (HPA) axis. Ngokuphendula ezicini ezicindezelayo, i-HPA axis ngokungaqondile inegalelo ekuqongeleleni okuphezulu kwe-cortisol kanye ne-dehydroepiandrosterone (DHEA), kanti amazinga aphansi e-DHEA ayimbangela yezinkinga eziningi zengqondo, zomzimba kanye nezobulili.
Ukusetshenziswa Komkhiqizo We-Turmeric + Utamatisi Odakiwe WaseNingizimu Afrika
Idatha ye-futuremarketinsights yembula ukuthi usayizi wemakethe yomhlaba wonke we-turmeric ungafinyelela ku-USD 4,419.3 million ngo-2023. Njengoba ikhula ku-CAGR engu-5.5% ngesikhathi sokubikezela (2023-2033), imakethe iyonke izoba nenani elingaphezu kuka-USD 7,579.2 million ngo-2033.
Okwamanje, usayizi wemakethe yomhlaba wonke ye-intoxicant extract yaseNingizimu Afrika ungafinyelela ku-USD 698.0 million ngo-2023 futhi kulindeleke ukuthi ufinyelele ku-USD 1,523.0 million ngo-2033. Ikhula ku-CAGR engu-8.1% ngesikhathi sokubikezela (2023-2033). Umphumela wokubambisana kwe-turmeric ne-intoxicant yaseNingizimu Afrika kuye kwafakazelwa ukuthi unezinzuzo ezibalulekile zezempilo futhi usetshenziswa emikhiqizweni eyahlukahlukene.
Impilo ye-Justgoodkungenziwa ngezifiso ngobuningi
(1) Isithasiselo esiqukethe i-turmeric kanye ne-hepatica yaseNingizimu Afrika, esingafakwa emanzini ashisayo noma ubisi bese sidliwa ndawonye. Siqinisa amasosha omzimba, amandla kanye nokukhuthazela, silwa nomkhuhlane kanye nomkhuhlane, sithuthukisa ukugaya ukudla kanye nokubona.
(2) Isengezo esiqukethe i-curcumin kanye notamatisi onamakhanda aseNingizimu Afrika, umkhiqizo ungagcina abantu begcwele amandla, usize ekuqiniseni isimo sengqondo, futhi uqinisekise impilo yamalunga nezinye izingxenye zomzimba.
(3) Ingxube yezitshalo equkethe i-hepatica ne-curcumin yaseNingizimu Afrika, eqeda ukucindezeleka okubangelwa ukucindezeleka futhi igcine isimo sengqondo esijabulisayo.
(4) Iziphuzo eziqukethe i-turmeric kanye nogwayi oludakayo lwaseNingizimu Afrika, ezingenashukela owengeziwe, zisiza abantu ukuthuthukisa ukucabanga kwabo nokugcina ukugxilisa ingqondo.
Isikhathi sokuthunyelwe: Novemba-21-2024