I-Astaxanthin (3,3'-Dihydroxy-Beta, beta-carotene-4,4'-dione) yi-carotenoid, ehlukaniswe njenge-lutein, etholakala ezinhlobonhlobo zama-microorganisms nezilwane zasolwandle, ekuqaleni ezahlukaniswe nama-lobster by Kuhn naseSorensen. Kuyinto umbala onyibilikayo obonakala orenji ebomvu ngokujulile ngombala futhi awunawo amavithamini asebenza ngomzimba womuntu.
Imithombo yemvelo ye-ataxanthin ifaka phakathi i-algae, imvubelo, i-salmon, i-trout, i-krill ne-crayfish. I-Astaxancanthin ikakhulukazi isuselwa ku-Fishe Yeast, i-algae ebomvu kanye ne-chemical synthesis. Eminye yemithombo engcono kakhulu yemvelo i-ataxancanthin iyimvula i-chlorella ebomvu yemvula, ngokuqukethwe kwe-astaxanthin okungama-3.8% (ngesisindo esomile), futhi ama-salmon asendle nawo anemithombo emihle ye-astaxanthin. Ukukhiqizwa okwenziwayo kusengumthombo oyinhloko we-ataxanthin ngenxa yezindleko eziphakeme zokutshala okulinganiselwe kwe-Rhodococcus Rainieri. Umsebenzi wezinto eziphilayo ze-Sytaxancanthin ngamaphesenti angama-50 kuphela walokho kwemvelo antaxanthin.
I-Astaxanthin ikhona njengama-stereoisomers, ama-isometric isomers, amafomu wamahhala futhi acacisiwe, anama-stereoisomers (3s, 3's) kanye (3r, 3'R I-Rhodococcus Raini ikhiqiza (3s, 3's) -Isomeresi kanye ne-Fishe Yempi ikhiqiza (3r, 3'r) -Isome.
I-Astaxanthin, ukushisa komzuzu
I-Astaxanthin iyisithako senkanyezi ekudleni okusebenzayo kwezibalo zikaJapan.FTA ngezimemezelo zokudla ezisebenzayo eJapan ngo-2022 zibalwa ama-astaxanthin ezinhlamvu zezempilo, ukunakekelwa kwamehlo, ukukhathala ukukhathala, kanye nokwenza ngcono umsebenzi wokuqonda.
Emiklomelo ka-2022 no-2023 Asia izithako zokudla okunempilo,Impilo ye-Justgood I-Natural Astaxancanthin Ithambekele njengesithako esihle kakhulu sonyaka iminyaka emibili elandelanayo, isithako esihle kakhulu kuthrekhi yokusebenza kwengqondo ngo-2022, futhi isithako esisezingeni eliphansi kwi-Assian FethleCleints Awards - Ithrekhi Enempilo Yokuguga ngo-2024.
Eminyakeni yamuva nje, ucwaningo lwezifundo ku-Astaxanthin luqale nokushisa. Ngokusho kwemininingwane eshicilelwe, ekuqaleni kuka-1948, kwakukhona izifundo ku-Astaxanthin, kepha ukunakwa kuncishiswe ngo-2011, kuqale ukugxila ku-Astaxanthin, futhi ngaphezulu kwe-200 ngonyaka we-2020, nangaphezulu kwama-400 ngonyaka we-2021.
Umthombo wesithombe: Pubmed
Mayelana nemakethe, ngokusho kwemakethe yemakethe yesikhathi esizayo, usayizi wemakethe wesikhathi esizayo, kulinganiselwa ukuthi usayizi wemakethe ka-Astaxanthin ulinganiselwa ku-203.2 million ku-2065.0 wezigidi ezingama-203.0 ngonyaka ka-2034, ngesikhathi se-9.3% ngesikhathi sokubikezela (2024-2034).
Umthamo ophakeme we-antioxidant
Isakhiwo esiyingqayizivele sika-Astaxanthin sikunikeza amandla aphezulu we-antioxidant. I-Astaxanthin iqukethe izibopho eziphindwe kabili ezihlanganisiwe, amaqembu e-hydroxyl kanye ne-ketone, futhi zombili i-lipophilic ne-hydrophilic. I-conjugated Double Bond emaphakathi nendawo inikezela ngama-elektroni futhi aphendule ngama-radicals wamahhala ukuze uyiguqule ibe yimikhiqizo ezinzile kakhulu futhi iqede ukusabela kwama-chain mahhala ezintweni ezahlukahlukene. Umsebenzi wayo wezinto eziphilayo uphakeme kunalokho kwamanye ama-antioxidants ngenxa yekhono lawo lokuxhuma kulwelwesi lwamaselula kusuka ngaphakathi.
Indawo ye-Astaxanthin namanye ama-antioxidants kuma-membranes weseli
I-Astaxanthin inamandla amakhulu e-antioxidant I-Astaxanthin ivimbela ukwakheka kwe-ROS futhi ilawula inkulumo ye-enzymes ephendulayo yokuphendula ye-oxidative, enjenge-heme oxygenase-1 (ho-1), okuwuphawu lwe-NRF2, olubopha kwi-antioxidant ephendula isifunda esifundeni se-Detoxifing Metabolism ama-enzymes.
Uhla oluphelele lwezinzuzo ze-astaxancanthin kanye nezinhlelo zokusebenza
1) Ukuthuthuka komsebenzi wokuqonda
Ucwaningo oluningi lukuqinisekisile ukuthi i-ataxanthin ingabambezela noma ithuthukise ukusilela kwengqondo okuhambisana nokuguga noma ukuzalela i-pathophysiology yezifo ezahlukahlukene ze-neurodegenerative. I-Astaxanthin ingawela isithiyo segazi-ubuchopho, futhi cwaningo selukhombisile ukuthi i-ataxanthin yokudla i-ataxanthin iqongelela nge-hippocampus kanye ne-cerebral cortex ye-rat ubuchopho ngemuva kokudla okukodwa, okungathinta ukulungiswa kanye nokwenza ngcono umsebenzi wokuqonda. I-Astaxanthin ikhuthaza ukuvuselelwa kwamaseli ezinzwa futhi yandisa ukuvezwa kohlobo lwe-glial fibrillary acibric protein (GFAP), iprotheni ye-microtubule), amaprotheni ahambisana ne-Neurotrophic (i-proteins
I-Justgood Health Astaxancanthin Caplules, nge-Cytisine kanye ne-astaxanthin kusuka ku-Red Algae Ihlathi lemvula, Synergize ukuthuthukisa umsebenzi wengqondo wobuchopho.
2) Ukuvikelwa kwamehlo
I-Astaxanthin inomsebenzi we-antioxidant ongathathi hlangothi ama-molecule wamahhala we-oxygen futhi anikeze ukuvikela ngamehlo. I-Astaxanthin isebenza ngokuxhumana namanye ama-carotenoids asekela impilo yamehlo, ikakhulukazi i-lutein ne-zexanthin. Ngaphezu kwalokho, i-astaxanthin yandisa izinga lokugeleza kwegazi esweni, livumele igazi livuselele kabusha i-retina kanye nezicubu zamehlo. Ucwaningo lukhombisile ukuthi i-Astaxanthin, ngokuhlanganiswa namanye ama-carotenoids, ivikela amehlo kumonakalo ngaphesheya kwe-solar spectrum. Ngaphezu kwalokho, i-Astaxanthin isiza ukukhipha amehlo ngamehlo nokukhathala okubonakalayo.
I-Justgood Health Blue Sluept Supply Softgels, Izithako ezibalulekile: I-lutein, zeaxanthin, astaxanthin.
3) Ukunakekelwa kwesikhumba
Ukuxineka nge-oxidative kuyinto eyisisekelo esibalulekile sokuguga kwesikhumba somuntu nomonakalo wesikhumba. Indlela yokuhlanza okuphakathi (ukulandelana kwezikhathi) kanye nokuguga (ukukhanya) ukukhiqizwa kwe-ROS, ngobuhlakani ngokusebenzisa i-axebolism ye-oxidative, kanye ne-extorically ngokusebenzisa imisebe yelanga ye-ultraviolet (UV). Imicimbi exidative ekugugeni kwesikhumba ifaka ukulimala kwe-DNA, izimpendulo zokuvuvukala, ukuncishiswa kwama-antioxidants, kanye nokukhiqizwa kwama-matrix metalporebonanases (MMPs) anciphisa i-collagen kanye ne-elastin kwi-dermis.
I-Astaxanthin ingavimbela ngempumelelo ukulimala kwama-oxidatical-oxidative mahhala nokungeniswa kwe-MMP-1 esikhunjeni ngemuva kokuvezwa kwe-UV. Ucwaningo lukhombisile ukuthi i-ataxanthin evela ku-erythrocystis rainbowensis ingakhulisa okuqukethwe okuhlangene ngokuvimbela ukuvezwa kwe-MMP-1 ne-MMP-3 ku-Dermal Fibroblasts yabantu. Ngaphezu kwalokho, i-astaxanthin inciphisa ukulimala kwe-DNA okubangelwa i-UV kanye nokulungiswa kwe-DNA kumaseli avezwa ngemisebe ye-UV.
I-Justgood Health njengamanje yenza izifundo eziningana, kufaka phakathi amagundane angenazinwele kanye novivinyo lwabantu, konke okukhonjiswe ukuthi i-ataxanthin inciphisa ukulimala kwezendlalelo ezijulile zesikhumba, njengokugqwala kwesikhumba, isikhumba sakwamisa kanye nemibimbi.
4) Ukudla Kwezemidlalo
I-Astaxanthin ingasheshisa ukulungisa ngemuva kokuzivocavoca. Lapho abantu bevivinya umzimba noma besebenza, umzimba ukhiqiza inani elikhulu le-ros, okuthi, uma kungasuswa ngesikhathi, kungalimaza izicubu futhi kuthinte ukululama ngokomzimba, ngenkathi umsebenzi oqinile we-antioxidant oqinile ungasusa i-ros ngesikhathi nokulungisa izicubu ezilimele ngokushesha.
I-Justgood Health ingenisa inkimbinkimbi yayo entsha ye-ataxanthin, inqwaba yama-glyseces glycecephosphate, i-Vitamin B6 (i-pyridoxine), ne-astaxanthin ehlisa ubuhlungu bemisipha nokukhathala ngemuva kokuzivocavoca. The formula is centered around Justgood Health's Whole Algae Complex, which delivers natural astaxanthin that not only protects muscles from oxidative damage, but also enhances muscle performance and improves athletic performance.
5) Impilo yenhliziyo
Ukuxineka okuxakile nokuvuvukala kubonakala nge-pathophysiology yesifo se-atherosclerotic cardiovascular isifo. Umsebenzi we-antioxidant omuhle kakhulu we-ataxanthin angavimbela futhi athuthukise i-atherossteosis.
I-Justgood Health Triple Feral Amandla wemvelo antaxancanthin softgels asiza ukugcina impilo yenhliziyo esebenzisa i-ataxancanthin etholwa ku-astaxanthin, izithako eziphambili zazo ezibandakanya u-ataxanthin, i-organic virgin kakhukhunathi uwoyela kanye ne-tocophols yemvelo.
6) Umthethonqubo Womzimba
Amaseli amasosha omzimba azwela kakhulu ngomonakalo omkhulu we-radical. I-Astaxanthin ivikela ukuvikela amasosha omzimba ngokuvimbela ukulimala kwamahhala okukhulu. Ucwaningo luthole ukuthi i-Astaxanthin emangqamuzaneni abantu ukukhiqiza i-Immunoglobulins, emzimbeni womuntu u-Ataxanthin Supply amaviki awu-8, amaseli we-Astaxanthin ancishisiwe, amaprotheni e-C-Reactive ancishisiwe.
I-Astaxancanthin Softgels, i-Astaxanthin, sebenzisa ukukhanya kwelanga kwemvelo, amanzi ahlungile ama-lava kanye namandla elanga ukukhiqiza i-ataxanthin emsulwa, ongasiza ekuthuthukiseni ukungavikeleki, ukuvikela umbono kanye nempilo ehlanganyelwe.
7) Susa ukukhathala
A 4-week randomized, double-blind, placebo-controlled, two-way crossover study found that astaxanthin promoted recovery from visual display terminal (VDT)-induced mental fatigue, attenuating elevated plasma phosphatidylcholine hydroperoxide (PCOOH) levels during both mental and physical activity. Isizathu singaba ngumsebenzi we-antioxidant kanye nendlela yokulwa nokuvuvukala kwe-astaxanthin.
8) Ukuvikelwa kwesibindi
I-Astaxanthin inemiphumela yokuvimbela futhi yokuzivikela ezinkingeni zempilo ezinjengesibindi FIBROSS, Isibindi Ischemia-ReperFusion Ukulimala, kanye na-nafld. I-Astaxanthin ingalawula izindlela ezahlukahlukene zokusayina, njengokunciphisa umsebenzi we-JNK nomsebenzi we-ERK-1 ukuthuthukisa ukumelana ne-insulin ye-insulin, nokulawula phansi i-TGF-β1 / smad3 ukunxenxa i-HSCS activation kanye ne-fibrosis yesibindi.
Isimo semithethonqubo ezweni ngalinye
EChina,astaxanthin Kusuka emthonjeni we-rainbow red algae angasetshenziswa njengesithako esisha sokudla okujwayelekile (ngaphandle kokudla kwengane), ngaphezu kwalokho, i-United States, iCanada, iCanada neJapan nakho kuvumela i-Astaxanthin ukuthi isetshenziswe ekudleni.
Isikhathi sePosi: Dec-05-2024