I-Artemether CAS 71963-77-4 I-Artemisia Annua Extract

I-Artemether iyi-lactone ye-sesquiterpene etholakala ezimpandeni zeI-Artemisia ngonyaka, ngokuvamile eyaziwa ngokuthi umhlonyane omnandi.Iwumuthi onamandla wokulwa nomalaleveva osetshenziselwa ukwelapha nokuvimbela umalaleveva.I-Artemisinin, umanduleli we-artemether, yaqala ukukhishwa esitshalweni ngeminyaka yawo-1970, futhi ukutholakala kwayo kwazuza umcwaningi waseShayina u-Tu Youyou uMklomelo KaNobel Kwezokwelapha ngo-2015.

I-Artemether isebenza ngokubhubhisa amagciwane abangela umalaleveva.Umalaleveva ubangelwa i-protozoan parasite ebizwa ngokuthi i-Plasmodium, etheleleka kubantu ngokulunywa omiyane besifazane abanalesi sifo.Lapho sezingaphakathi emzimbeni womuntu, lezi zilokazane zanda ngokushesha esibindini nasemangqamuzaneni abomvu egazi, zibangele imfiva, amakhaza nezinye izimpawu ezinjengomkhuhlane.Uma ungelashwa, umalaleveva ungabulala.

I-Artemether iphumelela kakhulu ekulweni nezinhlobo ezingazweli emishanguzweni ye-Plasmodium falciparum, ebangela iningi lokufa okuhlobene nomalaleveva emhlabeni wonke.Iphinde isebenze ngokumelene nezinye izinhlobo ze-Plasmodium parasites ezibanga umalaleveva.I-Artemether ivamise ukunikezwa ngokuhlanganyela nezinye izidakamizwa, njenge-lumefantrine, ukuze kwehliswe ingozi yokungazweli emthini.

Ngaphandle kokusetshenziswa kwayo njengesidakamizwa esilwa nomalaleveva, i-artemether iphinde yatholakala inezinye izici zokwelapha.Ucwaningo luye lwabonisa ukuthi ine-anti-inflammatory, anti-tumor, kanye ne-anti-viral.Isetshenziselwe ukwelapha isifo samathambo, i-lupus, nezinye izifo ze-autoimmune.Iphinde yaphenywa ngamakhono ayo okwelapha i-COVID-19, nakuba ucwaningo olwengeziwe ludingeka ukuze kuqinisekiswe ukusebenza kwayo kahle.

I-Artemether ngokuvamile iphephile futhi ibekezelelwa kahle uma isetshenziswa njengoba iqondiswe.Nokho, njengazo zonke izidakamizwa, kungabangela imiphumela engemihle.Imiphumela emibi evame kakhulu ye-artemether ihlanganisa isicanucanu, ukuhlanza, isiyezi, nobuhlungu bekhanda.Ezimweni ezingavamile, kungabangela ukusabela okubi kakhulu, njengokushaya kwenhliziyo, ukuquleka, nokulimala kwesibindi.

Sengiphetha, i-artemether iyisidakamizwa esinamandla sokulwa nomalaleveva esiguqule ukwelapha nokuvimbela umalaleveva.Ukutholwa kwayo kusindise izimpilo eziningi futhi kwazuza ukuqashelwa komphakathi wesayensi.Ezinye izici zayo zokwelapha ziyenza ibe umuntu othembisayo ekwelapheni ezinye izifo.Nakuba ingabangela imiphumela engemihle, izinzuzo zayo zidlula kude ubungozi bayo uma isetshenziswa ngaphansi kokuqondisa kwezokwelapha.
Amafomu omthamo asetshenziswa kakhulu ahlanganisa amaphilisi, amaphilisi kanye nemijovo.Izinhlobo zezidakamizwa ziyimithi elwa nomalaleveva, futhi ingxenye enkulu i-artemether.Uhlamvu oluyimbangela lwamaphilisi e-artemether kwakungamaphilisi amhlophe.Umlingiswa we-artemether capsule yi-capsule, okuqukethwe kwayo okuyimpushana emhlophe;Uhlamvu lwesidakamizwa lomjovo we-artemether alunambala ukuya kuwoyela ophuzi okhanyayo - njengoketshezi.